Creating a centralized database for disclosing conflicts of interest (COI) is an easy sell. Deciding who is responsible and accountable for its funding and support is a much harder problem.
Funder-sponsored journals raise important conflict of interest questions, and may be fundamentally untenable in an industry that requires independent third-party evaluation of research reports.
A lurid story of intramural hijinks at the FDA shows how far from mission an organization can drift when it gets its priorities wrong.
Registering clinical trials after enrollment has commenced may lead to the perception that medical researchers are peeking.